Department of Biotechnology

DBT Funded M Sc Program, DST FIST sponsored Department, UGC SAP-DRS-II

Research Papers Published

• "A novel kinase mutation in VEGFR-1 predisposes its aC-helix/activation loop towards allosteric activation: Atomic insights from protein simulation" European journal of human genetics, 24(345): 1287 -1293 {ISSN: iSSN: 1018} Impact Factor= 4
• "Irigenin, a novel lead from Western Himalayan chemiome inhibits Fibronectin-Extra Domain A induced metastasis in Lung cancer cells" scientific reports, 6(154): 1 -13 {ISSN: iSSN 2045-} Impact Factor= 5
• "Bioactive supra decorated thiazolidine-4-carboxylic acid derivatives attenuate cellular oxidative stress by enhancing catalase activity" Physical Chemistry Chemical Physics, 22(2020): 7942 -7951 {ISSN: 1463-9076} Impact Factor= 3.4
• "Lung cancer cell-derived EDA-containing fibronectin induces an inflammatory response from monocytes and promotes metastatic tumor microenvironment." Journal of Cellular Biochemistry, 122(5): 562 -576 Impact Factor=
• "Genetic Analysis of colorectal carcinoma using high throughput SNP genotyping technique within the population of Jammu and Kashmir." Molecular Biology Reports, 48(8): 5889 -5895 Impact Factor=
• "Evaluation of 17 genetic variants in association with leukemia in the north Indian population using MassARRAY Sequenom" Journal of Biochemical and Molecular Toxicology, 35(7): e22792 -e22792 Impact Factor=
• "D224V and S128Y mutation in FSHRED influence thumb movement differentially: An intricate insight gained by short-term molecular dynamics simulation." Journal of cellular Biochemistry, 120(5): 7701 -7710 Impact Factor=
• "Investigating binding tendency, stability of Sulforaphane-N-acetyl cysteine in the active site of histone deacetylase 2 (HDAC2) and testing its cytotoxicity against distinct cancer lines through stringent molecular dynamics, DFT and cell based assays" Chemical Biology & Drug Design, 98(3): 63 -76 Impact Factor=
• "Atomic insight into the altered O6-Methylguanine-DNA methyltransferase protein architecture in gastric cancer" Plos One, 10(1): e0127741 -e0127741 Impact Factor=
• "Tectorigenin ablates the inflammation-induced epithelial–mesenchymal transition in a co-culture model of human lung carcinoma." Pharmacological Reports, 67(2): 382 -387 Impact Factor=
• "Affinity proteomics led identification of vimentin as a potential biomarker in colon cancers" Molecular Omics, 11(1): 159 -169 Impact Factor=
• "Dissection of paracrine/autocrine interplay in lung tumor microenvironment mimicking cancer cell-monocyte co-culture models reveals proteins that promote inflammation and metastasis" BMC Cancer, 23(1): 926 -936 {ISSN: 1471-2407} Impact Factor= 3.8
• "Ala307Thr variation modulates FSHR structure and impairs its binding affinity for FSH: Implications in polycystic ovarian syndrome" Cell Biochemistry and Function, 41(6): 633 -641 {ISSN: 1099-0844} Impact Factor= 3.6
• "Shielding and nurturing: Fibronectin as a modulator of cancer drug resistance." Journal of Cellular Physiology, 238(8): 1651 -1669 {ISSN: 1097-4652} Impact Factor= 5.6
• "Identification of novel inhibitors of tetranectin–plasminogen interaction to suppress breast cancer invasion: an integrated computational and cell-based investigation." Journal of Biomolecular Structure and Dynamics, 41(24): 15023 -15032 {ISSN: 0739-1102} Impact Factor= 4.4

Research Projects Details: